GermGuardian AC5350B 4-in-1 HEPA Air Purifier – With UV Light Sanitizer

Illnesses and disease come from pollution, everyone on the planet knows that. Small nasty airborne particles are harmful to the respiratory system, especially lungs. If a human is living in very bad air, he has a chance of getting lung cancer. Lung cancer is one of the worst cancers you can get and once you get it your chances for survival are close to zero.

Today, I’m going to test and review the GermGuardian AC5350B air purifier. This is an air purifier that uses a 4-in-1 filtration system and comes with some innovations that are in some way typical for GermGuardian air purifiers. Keep reading and find out how good it is and if it is worth buying.

GermGuardian AC5350B 28-inch 4-in-1 True HEPA Filter Air Purifier

Because of health, you should invest in a decent air purifier. There are many brands on the market, and all of them are more or less efficient. All of them have different features and properties. At the same time, all of them are working on the same way, sucking the lousy air in and releasing the fresh air. The performance of that job is in a correlation with the technology and parts used in air purifier manufacturing.

GermGuardian AC5350B Specifications

Below is a complete list of important specifications and features included on the GermGuardian AC5350B Air Purifier:

Manufacturer Guardian Technologies
Model AC5350B
Dimensions 9.06 x 6.69 x 27.56 inches
Filters Pre-filter and Charcoal Filter, True HEPA, and UV-C Light
UV-C Yes
Coverage 167 sq. ft.
CADR Dust 114, Pollen 127, and Smoke 108
Warranty 5-year Limited
User manual PDF

GermGuardian AC5350B Review

q? encoding=UTF8&ASIN=B00OLBR084&Format= SL250 &ID=AsinImage&MarketPlace=US&ServiceVersion=20070822&WS=1&tag=apfpi 20&language=en USGermGuardian AC5350B 28-inch 4-in-1 True HEPA Filter Air Purifier

Feature Info
Captures Allergens True HEPA captures 99.97% of Pollen, Dust Mites, Pet Dander and Mold.
Fights Germs UV-C Power kills airborne Bacteria, Viruses and Mold Spores.
Reduces Odors Charcoal filter Reduces common odors from Pets, Smoking and Cooking.

If you ask GermGuardian customers which air purifier to pick the majority of them will tell you to go with GermGuardian brand. Customers are very satisfied with the brand. The reason behind the satisfaction lays in years of experience in an air purifying field.

GermGuardian made many air purifying models, and at this moment they have several types of the air purifiers on the market. Some of the air purifiers are built for large rooms, some for small rooms, but all of them have a high performance in filtering the air.


The GermGuardian AC5350B is a big air purifier, but it will not take too much of the space in the room because it is designed as a high tower. In fact, the air purifier is 28 inches tall. That unique design allows you to place the GermGuardian AC5350B air purifier in any corner of the room or if you want excellent performance, you can also place it in the middle of the room beside a table.

The weight of the whole device is only 11 pounds which means you can quickly move it to the new room. This air purifier is not made for mobility, but with a small effort, you can move it from one room to other without a problem. In that way, you can have a whole house filtered and filled with fresh, clean air.

Display Features

Such a modern design needs a stylish display. On display, you can choose various settings. You can control the speeds of the fans and if you wish slower or faster filtration. If the air in the room is not heavily polluted, then the low speed is the priority.

You can also choose timer and select for how long you wish the air purifier to work and after the time runs out the air purifier will shut down. In this way, you can save some extra energy.

For fighting germs and other nasty microorganisms, there is a UV mode which you can turn on and off; however you like. The most important feature on display is UV reset and HEPA filter reset. These two display indicators will tell you when to change filters and UV bulb.

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4 in 1 Filtration System

The GermGuardian AC5350B performance lays in a unique 4 in 1 filtration system. Nothing can get away from this filtration system. Because of that GermGuardian claims that the air purifier is capable of removing 99.9% of airborne particles. That number means that everything is captured, pet dander, pet hair, mold spores, germs, dust, smoke, pollen and other allergens.

Prefilter with Charcoal Layer

First, the air moves through the prefilter. Prefilter will capture large particles like pet hair, large dust and other large particles that may make primary filter dirty too fast. Prefilter has a charcoal layer which will remove smoke, odors, cooking fumes, and other unwanted smells in the house.

True HEPA Filter

The primary filter is true HEPA filter which means that it has a certificate that guarantees that this filter is capable of removing dust mites, pollen, dander, dust and many other small airborne particles that may trigger your allergies. True HEPA filter is the latest most advanced filter on the market, and GermGuardian knows that.

UV-C Light

The last filtration method in the GermGuardian AC5350B is the UV-C light that has the power to kill germs, influenza viruses, rhinovirus, pneumonia, and staphylococci. UV-C light requires titanium dioxide to be activated to decompose remaining molecules of the nasty germs.

Because of such powers and advanced technology that can even kill germs doctors recommend this product to all asthma patients and people who suffer from allergic reactions triggered by dust or other airborne particles.

Quiet at Work and Energy Efficient

The GermGuardian AC5350B is very quiet when working especially if you use a slow speed. And slow speed is more than enough while you sleep. In other words, you can enjoy the fresh air in a bedroom while you sleep. The fresh air will make your night sleep better, and in the morning you will be refreshed like never before.

At the same time this product has Energy star certificate which means that even if you run this device for a whole night, you will not spend lots of money. And since this air purifier has power to keep you healthy in a long run you are making money by running it. The more you run it, the fewer chances are you will get illnesses linked to the air pollution.

Replacement Filters for GermGuardian AC5350B

You should always use original replacement filters recommended by Guardian Technologies. And for this model, you can choose to replace whole filtering section or just preliminary filter with a carbon layer. If you need to replace HEPA filter then I highly suggest to replace whole filtration system, you should buy a package with a True HEPA filter and prefilter. But in case your prefilters get dirty, or the charcoal layer is not working correctly, not removing bad odors then you can buy prefilters which are not expensive but in return can make your house free from bad smells.

Having a new prefilter is also important to keep true HEPA filter free from dirt. By replacing prefilters, you can prolong the life of the true HEPA filter.

q? encoding=UTF8&ASIN=B003AKIGFS&Format= SL250 &ID=AsinImage&MarketPlace=US&ServiceVersion=20070822&WS=1&tag=apfpi 20&language=en USGermGuardian Air Purifier Filter FLT5000 Genuine HEPA Replacement Filter

Feature Info
Multiple Levels of Cleaning Multiple levels of cleaning include HEPA, Pre-Filter and a Charcoal layer to help improve indoor air quality.
Features True HEPA Filter captures 99.97% of dust and allergens as small as .3 microns such as household dust, pet dander, mold spores and plant pollens.

Pros and Cons

To revise, here are advantages and disadvantages of the GermGuardian AC5350B:


  • High-Quality Material
  • Made from Durable ABS Plastic
  • Cool Unique Tower Design Fits Every Room
  • Powerful Filtration System that Can Kill Germs
  • Ideal Choice for Asthma Patients and People Who Suffer from Allergies
  • Doctors Recommend this Product
  • Energy Saver
  • UV Mode Indicator
  • Filter Replacement Indicator


  • Filters will need to be replaced every 6 to 8 months. But if you replace prefilter more often maybe the main filter will last longer.

Final Thoughts

The price for GermGuardian AC5350B is maybe too high for some people, but if you are suffering from asthma or allergic reactions to airborne particles, then the amount for this device is very small. GermGuardian AC5350B is recommended by doctors which means that there are scientific proves that this device can help you fight a polluted air.

The air is not getting cleaner on its own, in fact, it gets more polluted as we speak, the only way to keep it clean is to shut down windows and doors and turn on the air purifier.

With GermGuardian AC5350B you can do just that, turn it on and keep it running as long as the air in the room is not clean. In the process you will not spend much money on electricity because the AC5350B is the energy saver, it runs on low wattage which makes sure that no extra energy is spent. Also, you can use a timer to shut down the air purifier automatically and in that way keep the electric bill even smaller.

Update Log

June 28, 2021 – I have improved the article design, added specifications, and rechecked some information about the product.

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